| Accession | TIGR02914 |
| Name | EpsI_fam |
| Function | EpsI family protein |
| Gene Symbol | epsI |
| Trusted Cutoff | 42.80 |
| Domain Trusted Cutoff | 42.80 |
| Noise Cutoff | 42.45 |
| Domain Noise Cutoff | 42.45 |
| Isology Type | equivalog_domain |
| HMM Length | 174 |
| Mainrole Category | Transport and binding proteins |
| Subrole Category | Unknown substrate |
| Gene Ontology Term | GO:0003674: molecular_function molecular_function |
| | GO:0005575: cellular_component cellular_component |
| | GO:0008150: biological_process biological_process |
| Author | Haft DH |
| Entry Date | Apr 5 2006 10:48AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | In Methylobacillus sp strain 12S, EpsI is encoded immediately downstream of the multiple-membrane-spanning putative transporter EpsH, and is predicted to be a periplasmic protein involved in, but not required for, expression of the exopolysaccharide methanolan. In a number of other species, protein homologous to EpsI is encoded either next to EpsH or, more often, combined in a fused gene. We have proposed renaming EpsH, or the EpsHI fusion protein, to exosortase, based on its phylogenetic association with the PEP-CTERM proposed protein targeting signal. |
| References | RN [1]
RM PMID: 16930487
RT Exopolysaccharide-associated protein sorting in environmental organisms: the PEP-CTERM/EpsH system. Application of a novel phylogenetic profiling heuristic.
RA Haft DH, Paulsen IT, Ward N, Selengut JD
RL BMC Biol. 2006 Aug 24;4(1):29.
RN [2]
RM PMID: 12624205
RT Genes involved in the synthesis of the exopolysaccharide methanolan by the obligate methylotroph Methylobacillus sp strain 12S.
RA Yoshida T, Ayabe Y, Yasunaga M, Usami Y, Habe H, Nojiri H, Omori T
RL Microbiology. 2003 Feb;149(Pt 2):431-44. |
| Genome Property | GenProp0326: protein sorting system, PEP-CTERM/exosortase (generic) (HMM) |
| | GenProp0652: exopolysaccharide biosynthesis, exosortase A-associated (HMM-CLUST) |
