HMM Summary Page: TIGR02913

Functionprobable extracellular repeat, HAF family
Trusted Cutoff22.65
Domain Trusted Cutoff22.65
Noise Cutoff20.25
Domain Noise Cutoff20.25
Isology Typerepeat
HMM Length39
AuthorHaft DH
Entry DateMar 31 2006 1:31PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe HMM for this family detects a homology domain of about 40 amino acids. Member proteins always have a least two tandem copies and as many as seven. The spacing between repeats as defined here usually is four residues exactly. This repeat is named for a tripeptide motif HAF found in most members. Some members proteins are found in species with no outer membrane (archaea and Gram-positive bacteria) while others have C-terminal autotransporter domains that suggest that the repeat region is transported across the outer membrane. This domain seems likely to be an extracellular protein repeat.