HMM Summary Page: TIGR02907

Functionstage VI sporulation protein D
Gene SymbolspoVID
Trusted Cutoff169.85
Domain Trusted Cutoff169.85
Noise Cutoff34.95
Domain Noise Cutoff34.95
Isology Typeequivalog
HMM Length344
Mainrole CategoryCellular processes
Subrole CategorySporulation and germination
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0030436: asexual sporulation biological_process
AuthorHaft DH
Entry DateMar 21 2006 4:26PM
Last ModifiedFeb 14 2011 3:27PM
CommentSpoVID, the stage VI sporulation protein D, is restricted to endospore-forming members of the bacteria, all of which are found among the Firmicutes. It is widely distributed but not quite universal in this group. Between well-conserved N-terminal and C-terminal domains is a poorly conserved, low-complexity region of variable length, rich enough in glutamic acid to cause spurious BLAST search results unless a filter is used. The seed alignment for this model was trimmed, in effect, by choosing member sequences in which these regions are relatively short. SpoVID is involved in spore coat assembly by the mother cell compartment late in the process of sporulation.
ReferencesRN [1] RM PMID: 11325931 RT SpoVID guides SafA to the spore coat in Bacillus subtilis. RA Ozin AJ, Samford CS, Henriques AO, Moran CP Jr RL J Bacteriol. 2001 May;183(10):3041-9.
Genome PropertyGenProp0610: endospore formation marker gene set (HMM)