HMM Summary Page: TIGR02889

Functiongermination protein YpeB
Gene SymbolypeB
Trusted Cutoff303.55
Domain Trusted Cutoff303.55
Noise Cutoff73.45
Domain Noise Cutoff73.45
Isology Typeequivalog
HMM Length435
Mainrole CategoryCellular processes
Subrole CategorySporulation and germination
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0009847: spore germination biological_process
GO:0030436: asexual sporulation biological_process
AuthorHaft DH
Entry DateMar 13 2006 12:23PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family are YpeB, a protein usually encoded with the putative spore-cortex-lytic enzyme SleB and required, together with SleB, for normal germination. This family is retricted to endospore-forming species in the Firmicutes lineage of bacteria, and found in all such species to date except Clostridium perfringens. The matching phenotypes of mutants in SleB (called a lytic transglycosylase) and YpeB suggests that YpeB is necessary to allow SleB to function.
ReferencesRN [1] RM 10658652 RT Complete spore-cortex hydrolysis during germination of Bacillus subtilis 168 requires SleB and YpeB. RA Boland FM, Atrih A, Chirakkal H, Foster SJ, Moir A. RL Microbiology. 2000 Jan;146 ( Pt 1):57-64.
Genome PropertyGenProp0610: endospore formation marker gene set (HMM)