HMM Summary Page: TIGR02877

Functionsporulation protein YhbH
Gene SymbolyhbH
Trusted Cutoff467.95
Domain Trusted Cutoff467.95
Noise Cutoff282.90
Domain Noise Cutoff282.90
Isology Typeequivalog
HMM Length371
Mainrole CategoryCellular processes
Subrole CategorySporulation and germination
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0030436: asexual sporulation biological_process
AuthorHaft DH
Entry DateMar 8 2006 1:10PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein family, typified by YhbH in Bacillus subtilis, is found in nearly every endospore-forming bacterium and in no other genome (but note that the trusted cutoff score is set high to exclude a single high-scoring sequence from Nitrosococcus oceani ATCC 19707, which is classified in the Gammaproteobacteria). The gene in Bacillus subtilis was shown to be in the regulon of the sporulation sigma factor, sigma-E, and its mutation was shown to create a sporulation defect.
ReferencesRN [1] RM 14523133 RT Identification of sporulation genes by genome-wide analysis of the sigmaE regulon of Bacillus subtilis. RA Feucht A, Evans L, Errington J. RL Microbiology. 2003 Oct;149(Pt 10):3023-34. DR HAMAP; MF_01232; 17 of 77