HMM Summary Page: TIGR02871

Functionsporulation integral membrane protein YlbJ
Gene SymbolylbJ
Trusted Cutoff304.65
Domain Trusted Cutoff304.65
Noise Cutoff138.20
Domain Noise Cutoff138.20
Isology Typeequivalog
HMM Length363
Mainrole CategoryCellular processes
Subrole CategorySporulation and germination
Gene Ontology TermGO:0016021: integral to membrane cellular_component
GO:0030436: asexual sporulation biological_process
AuthorHaft DH
Entry DateMar 6 2006 3:55PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are found exclusively in Firmicutes (low-GC Gram-positive bacterial) and are known from studies in Bacillus subtilis to be part of the sigma-E regulon. Mutation leads to a sporulation defect, confirming that members of this protein family, YlbJ, are sporulation proteins. This protein appears to be universal among endospore-forming bacteria, but is encoded by a pair ORFs distant from eash other in Symbiobacterium thermophilum IAM14863.
ReferencesRN [1] RM 12662922 RT The sigmaE regulon and the identification of additional sporulation genes in Bacillus subtilis. RA Eichenberger P, Jensen ST, Conlon EM, van Ooij C, Silvaggi J, Gonzalez-Pastor JE, Fujita M, Ben-Yehuda S, Stragier P, Liu JS, Losick R. RL J Mol Biol. 2003 Apr 11;327(5):945-72.
Genome PropertyGenProp0610: endospore formation marker gene set (HMM)