Accession | TIGR02862 |
Name | spore_BofA |
Function | pro-sigmaK processing inhibitor BofA |
Gene Symbol | bofA |
Trusted Cutoff | 53.35 |
Domain Trusted Cutoff | 53.35 |
Noise Cutoff | 34.00 |
Domain Noise Cutoff | 34.00 |
Isology Type | subfamily |
HMM Length | 83 |
Mainrole Category | Cellular processes |
Subrole Category | Sporulation and germination |
Gene Ontology Term | GO:0016020: membrane cellular_component |
| GO:0030436: asexual sporulation biological_process |
Author | Haft DH |
Entry Date | Mar 3 2006 1:59PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Members of this protein family are found only in endospore-forming bacteria, such as Bacillus subtilis and Clostridium tetani. Among such bacteria, it appears only Symbiobacterium thermophilum lacks a member of this family. The protein, designated BofA, is an integral membrane protein that regulates the proteolytic activation of the RNA polymerase sigma factor K. |
References | RN [1]
RM 11959848
RT A sporulation membrane protein tethers the pro-sigmaK processing enzyme to its inhibitor and dictates its subcellular localization.
RA Rudner DZ, Losick R.
RL Genes Dev. 2002 Apr 15;16(8):1007-18. |