HMM Summary Page: TIGR02860

Functionstage IV sporulation protein B
Gene SymbolspoIVB
Trusted Cutoff305.25
Domain Trusted Cutoff305.25
Noise Cutoff148.70
Domain Noise Cutoff148.70
Isology Typeequivalog
EC Number3.4.21.116
HMM Length402
Mainrole CategoryCellular processes
Subrole CategorySporulation and germination
Gene Ontology TermGO:0008236: serine-type peptidase activity molecular_function
GO:0030436: asexual sporulation biological_process
AuthorHaft DH
Entry DateMar 3 2006 9:39AM
Last ModifiedFeb 14 2011 3:27PM
CommentSpoIVB, the stage IV sporulation protein B of endospore-forming bacteria such as Bacillus subtilis, is a serine proteinase, expressed in the spore (rather than mother cell) compartment, that participates in a proteolytic activation cascade for Sigma-K. It appears to be universal among endospore-forming bacteria and occurs nowhere else.
ReferencesRM 10931284 RT Proteolysis of SpolVB is a critical determinant in signalling of Pro-sigmaK processing in Bacillus subtilis. RA Wakeley PR, Dorazi R, Hoa NT, Bowyer JR, Cutting SM. RL Mol Microbiol. 2000 Jun;36(6):1336-48.
Genome PropertyGenProp0610: endospore formation marker gene set (HMM)