HMM Summary Page: TIGR02853

Functiondipicolinic acid synthetase, A subunit
Gene SymboldpaA
Trusted Cutoff319.65
Domain Trusted Cutoff319.65
Noise Cutoff98.70
Domain Noise Cutoff98.70
Isology Typeequivalog
HMM Length287
Mainrole CategoryCellular processes
Subrole CategorySporulation and germination
Gene Ontology TermGO:0003824: catalytic activity molecular_function
GO:0030436: asexual sporulation biological_process
AuthorHaft DH
Entry DateMar 1 2006 2:59PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis predicted Rossman fold-containing protein is the A subunit of dipicolinic acid synthetase as found in most, though not all, endospore-forming low-GC Gram-positive bacteria; it is absent in Clostridium. The B subunit is represented by TIGR02852. This protein is also known as SpoVFA.
ReferencesDR PFAM; PF01488; Shikimate_DH RN [1] RM 8345520 RT Cloning, DNA sequence, functional analysis and transcriptional regulation of the genes encoding dipicolinic acid synthetase required for sporulation in Bacillus subtilis. RA Daniel RA, Errington J. RL J Mol Biol. 1993 Jul 20;232(2):468-83. RN [2] RM 8098035 RT Organization and nucleotide sequence of the Bacillus subtilis diaminopimelate operon, a cluster of genes encoding the first three enzymes of diaminopimelate synthesis and dipicolinate synthase. RA Chen NY, Jiang SQ, Klein DA, Paulus H. RL J Biol Chem. 1993 May 5;268(13):9448-65.
Genome PropertyGenProp0610: endospore formation marker gene set (HMM)