HMM Summary Page: TIGR02852

Functiondipicolinic acid synthetase, B subunit
Gene SymboldpaB
Trusted Cutoff229.00
Domain Trusted Cutoff229.00
Noise Cutoff102.20
Domain Noise Cutoff102.20
Isology Typeequivalog
HMM Length187
Mainrole CategoryCellular processes
Subrole CategorySporulation and germination
Gene Ontology TermGO:0003824: catalytic activity molecular_function
GO:0030436: asexual sporulation biological_process
AuthorHaft DH
Entry DateMar 1 2006 2:24PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family represent the B subunit of dipicolinic acid synthetase, an enzyme that synthesizes a small molecule that appears to confer heat stability to bacterial endospores such as those of Bacillus subtilis. The A and B subunits are together in what was originally designated the spoVF locus for stage V of endospore formation.
ReferencesDR PFAM; PF02441; Flavoprotein RN [1] RM 8345520 RT Cloning, DNA sequence, functional analysis and transcriptional regulation of the genes encoding dipicolinic acid synthetase required for sporulation in Bacillus subtilis. RA Daniel RA, Errington J. RL J Mol Biol. 1993 Jul 20;232(2):468-83. RN [2] RM 8098035 RT Organization and nucleotide sequence of the Bacillus subtilis diaminopimelate operon, a cluster of genes encoding the first three enzymes of diaminopimelate synthesis and dipicolinate synthase. RA Chen NY, Jiang SQ, Klein DA, Paulus H. RL J Biol Chem. 1993 May 5;268(13):9448-65.
Genome PropertyGenProp0610: endospore formation marker gene set (HMM)