HMM Summary Page: TIGR02851

Functionstage V sporulation protein T
Gene SymbolspoVT
Trusted Cutoff235.90
Domain Trusted Cutoff235.90
Noise Cutoff71.65
Domain Noise Cutoff71.65
Isology Typeequivalog
HMM Length180
Mainrole CategoryRegulatory functions
Subrole CategoryDNA interactions
Gene Ontology TermGO:0003700: sequence-specific DNA binding transcription factor activity molecular_function
GO:0006355: regulation of transcription, DNA-dependent biological_process
GO:0030436: asexual sporulation biological_process
AuthorHaft DH
Entry DateMar 1 2006 1:36PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are the stage V sporulation protein T (SpoVT), a protein of the sporulation/germination program in Bacillus subtilis and related species. The amino-terminal 50 amino acids are nearly perfectly conserved across all endospore-forming bacteria. SpoVT is a DNA-binding transcriptional regulator related to AbrB (See PFAM model PF04014).
ReferencesDR SWISSPROT; P37554; Bacillus subtilis DR PFAM; PF04014; SpoVT_AbrB RN [1] RM 8755877 RT A compartmentalized regulator of developmental gene expression in Bacillus subtilis. RA Bagyan I, Hobot J, Cutting S. RL J Bacteriol. 1996 Aug;178(15):4500-7. RN [2] RM 16159768 RT Independent and interchangeable multimerization domains of the AbrB, Abh, and SpoVT global regulatory proteins. RA Yao F, Strauch MA. RL J Bacteriol. 2005 Sep;187(18):6354-62.
Genome PropertyGenProp0610: endospore formation marker gene set (HMM)