| Accession | TIGR02846 |
| Name | spore_sigmaK |
| Function | RNA polymerase sigma-K factor |
| Gene Symbol | sigK |
| Trusted Cutoff | 298.65 |
| Domain Trusted Cutoff | 298.65 |
| Noise Cutoff | 278.75 |
| Domain Noise Cutoff | 278.75 |
| Isology Type | equivalog |
| HMM Length | 227 |
| Mainrole Category | Transcription |
| Subrole Category | Transcription factors |
| Gene Ontology Term | GO:0006352: transcription initiation, DNA-dependent biological_process |
| | GO:0016987: sigma factor activity molecular_function |
| | GO:0042173: regulation of sporulation resulting in formation of a cellular spore biological_process |
| Author | Haft DH |
| Entry Date | Feb 28 2006 1:43PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | The sporulation-specific transcription factor sigma-K (also called sigma-27) is expressed in the mother cell compartment of endospore-forming bacteria such as Bacillus subtilis. Like its close homolog sigma-E (sigma-29) (see TIGR02835), also specific to the mother cell compartment, it must be activated by a proteolytic cleavage. Note that in Bacillus subtilis (and apparently also Clostridium tetani), but not in other endospore forming species such as Bacillus anthracis, the sigK gene is generated by a non-germline (mother cell only) chromosomal rearrangement that recombines coding regions for the N-terminal and C-terminal regions of sigma-K. |
| Genome Property | GenProp0610: endospore formation marker gene set (HMM) |
