HMM Summary Page: TIGR02845

Functionstage V sporulation protein AD
Gene SymbolspoVAD
Trusted Cutoff411.80
Domain Trusted Cutoff411.80
Noise Cutoff123.90
Domain Noise Cutoff123.90
Isology Typeequivalog
HMM Length327
Mainrole CategoryCellular processes
Subrole CategorySporulation and germination
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0030436: asexual sporulation biological_process
AuthorHaft DH
Entry DateFeb 28 2006 1:19PM
Last ModifiedFeb 14 2011 3:27PM
CommentBacillus and Clostridium species contain about 10 % dipicolinic acid (pyridine-2,6-dicarboxylic acid) by weight. This protein family, SpoVAD, belongs to the spoVA operon that is suggested to act in the transport of dipicolinic acid (DPA) from the mother cell, where DPA is synthesized, to the forespore, a process essential to sporulation. Members of this protein family are found, so far, in exactly those species believed capable of endospore formation.
ReferencesRN [1] RM 16077113 RT Localization of SpoVAD to the inner membrane of spores of Bacillus subtilis. RA Vepachedu VR, Setlow P. RL J Bacteriol. 2005 Aug;187(16):5677-82.
Genome PropertyGenProp0610: endospore formation marker gene set (HMM)