HMM Summary Page: TIGR02842

Functioncytochrome o ubiquinol oxidase, subunit III
Gene SymbolcyoC
Trusted Cutoff223.75
Domain Trusted Cutoff223.75
Noise Cutoff214.00
Domain Noise Cutoff214.00
Isology Typeequivalog
EC Number1.10.3.-
HMM Length180
Mainrole CategoryEnergy metabolism
Subrole CategoryElectron transport
Gene Ontology TermGO:0008827: cytochrome o ubiquinol oxidase activity molecular_function
GO:0015990: electron transport coupled proton transport biological_process
GO:0016021: integral to membrane cellular_component
AuthorSelengut J
Entry DateFeb 28 2006 11:29AM
Last ModifiedFeb 14 2011 3:27PM
CommentCytochrome o terminal oxidase complex is the component of the aerobic respiratory chain which reacts with oxygen, reducing it to water with the concomitant transport of 4 protons across the membrane. Also known as the cytochrome bo complex, cytochrome o ubiquinol oxidase contains four subunits, two heme b cofactors and a copper atom which is believed to be the oxygen active site. This complex is structurally related to the cytochrome caa3 oxidases which utilize cytochrome c as the reductant and contain heme a cofactors, as well as the intermediate form aa3 oxidases which also react directly with quinones as the reductant.
Genome PropertyGenProp0618: cytochrome (quinone) oxidase, bo type (HMM)
GenProp0614: cytochrome c oxidase, mitochondrial, caa3-type (SUBFAM-EX)