HMM Summary Page: TIGR02824

Functionputative NAD(P)H quinone oxidoreductase, PIG3 family
Trusted Cutoff296.80
Domain Trusted Cutoff296.80
Noise Cutoff293.70
Domain Noise Cutoff293.70
Isology Typesubfamily
HMM Length325
Mainrole CategoryUnknown function
Subrole CategoryEnzymes of unknown specificity
Gene Ontology TermGO:0008152: metabolic process biological_process
GO:0016655: oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor molecular_function
AuthorHaft DH
Entry DateFeb 14 2006 10:49AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family are putative quinone oxidoreductases that belong to the broader superfamily (modeled by Pfam PF00107) of zinc-dependent alcohol (of medium chain length) dehydrogenases and quinone oxiooreductases. The alignment shows no motif of conserved Cys residues as are found in zinc-binding members of the superfamily, and members are likely to be quinone oxidoreductases instead. A member of this family in Homo sapiens, PIG3, is induced by p53 but is otherwise uncharacterized.
ReferencesDR PFAM; PF00107; ADH_zinc_N