HMM Summary Page: TIGR02823
Accession | TIGR02823 |
Name | oxido_YhdH |
Function | putative quinone oxidoreductase, YhdH/YhfP family |
Trusted Cutoff | 297.25 |
Domain Trusted Cutoff | 297.25 |
Noise Cutoff | 146.90 |
Domain Noise Cutoff | 146.90 |
Isology Type | subfamily |
HMM Length | 324 |
Mainrole Category | Unknown function |
Subrole Category | Enzymes of unknown specificity |
Gene Ontology Term | GO:0008152: metabolic process biological_process |
GO:0016655: oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor molecular_function | |
Author | Haft DH |
Entry Date | Feb 13 2006 1:40PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This model represents a subfamily of PF00107 as defined by Pfam, a superfamily in which some members are zinc-binding medium-chain alcohol dehydrogenases while others are quinone oxidoreductases with no bound zinc. This subfamily includes proteins studied crystallographically for insight into function: YhdH from Escherichia coli and YhfP from Bacillus subtilis. Members bind NADPH or NAD, but not zinc. |
References | RN [1] RM 15388933 RT Structure of Escherichia coli YhdH, a putative quinone oxidoreductase. RA Sulzenbacher G, Roig-Zamboni V, Pagot F, Grisel S, Salomoni A, Valencia C, Campanacci V, Vincentelli R, Tegoni M, Eklund H, Cambillau C. RL Acta Crystallogr D Biol Crystallogr. 2004 Oct;60(Pt 10):1855-62. RN [2] RT The crystal structure of hypothetical protein yhfP from Bacillus subtilis RA Min, T., Gorman, J., Shapiro, L. RL unpublished |