HMM Summary Page: TIGR02819
Accession | TIGR02819 |
Name | fdhA_non_GSH |
Function | formaldehyde dehydrogenase, glutathione-independent |
Gene Symbol | fdhA |
Trusted Cutoff | 636.95 |
Domain Trusted Cutoff | 636.95 |
Noise Cutoff | 425.15 |
Domain Noise Cutoff | 425.15 |
Isology Type | equivalog |
EC Number | 1.2.1.46 |
HMM Length | 397 |
Mainrole Category | Central intermediary metabolism |
Subrole Category | One-carbon metabolism |
Gene Ontology Term | GO:0018467: formaldehyde dehydrogenase activity molecular_function |
GO:0046292: formaldehyde metabolic process biological_process | |
Author | Haft DH |
Entry Date | Feb 8 2006 5:17PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Members of this family represent a distinct clade within the larger family of zinc-dependent dehydrogenases of medium chain alcohols, a family that also includes the so-called glutathione-dependent formaldehyde dehydrogenase. Members of this protein family have a tightly bound NAD that can act as a true cofactor, rather than a cosubstrate in dehydrogenase reactions, in dismutase reactions for some aldehydes. The name given to this family, however, is formaldehyde dehydrogenase, glutathione-independent. |