| Accession | TIGR02810 |
| Name | agaZ_gatZ |
| Function | D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit |
| Trusted Cutoff | 568.80 |
| Domain Trusted Cutoff | 568.80 |
| Noise Cutoff | 191.60 |
| Domain Noise Cutoff | 191.60 |
| Isology Type | equivalog |
| EC Number | 4.1.2.40 |
| HMM Length | 420 |
| Mainrole Category | Energy metabolism |
| Subrole Category | Sugars |
| Author | Haft DH |
| Entry Date | Jan 30 2006 2:52PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Aldolases specific for D-tagatose-bisphosphate occur in distinct pathways in Escherichia coli and other bacteria, one for the degradation of galactitol (formerly dulcitol) and one for degradation of N-acetyl-galactosamine and D-galactosamine. This family represents a protein of both systems that behaves as a non-catalytic subunit of D-tagatose-bisphosphate aldolase, required both for full activity and for good stability of the aldolase. Note that members of this protein family appear in public databases annotated as putative tagatose 6-phosphate kinases, possibly in error. |
| References | RN [1]
RM 11976750
RT Two class II D-tagatose-bisphosphate aldolases from enteric bacteria.
RA Brinkkotter A, Shakeri-Garakani A, Lengeler JW.
RL Arch Microbiol. 2002 May;177(5):410-9.
RN [2]
RM 8955298
RT Molecular analysis of the gat genes from Escherichia coli and of their roles in galactitol transport and metabolism.
RA Nobelmann B, Lengeler JW.
RL J Bacteriol. 1996 Dec;178(23):6790-5.
RN [3]
RM 10931310
RT Pathways for the utilization of N-acetyl-galactosamine and galactosamine in Escherichia coli.
RA Brinkkotter A, Kloss H, Alpert C, Lengeler JW.
RL Mol Microbiol. 2000 Jul;37(1):125-35. |
