| Accession | TIGR02804 |
| Name | ExbD_2 |
| Function | TonB system transport protein ExbD |
| Gene Symbol | expD |
| Trusted Cutoff | 123.45 |
| Domain Trusted Cutoff | 123.45 |
| Noise Cutoff | 86.35 |
| Domain Noise Cutoff | 86.35 |
| Isology Type | equivalog |
| HMM Length | 121 |
| Gene Ontology Term | GO:0006810: transport biological_process |
| | GO:0015570: energizer of outer membrane receptor-mediated transport activity molecular_function |
| Author | Haft DH |
| Entry Date | Jan 24 2006 10:54AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this family are Gram-negative bacterial inner membrane proteins, generally designated ExbD, related to the TolR family modeled by TIGRFAMs TIGR02801. Members always are encoded next to a protein designated ExbB (TIGR02797), related to the TolQ family modeled by TIGRFAMs TIGR02796. ExbD and ExbB together form a proton channel through which they can harness the proton-motive force to energize TonB, which in turn energizes TonB-dependent receptors in the outer membrane. TonB-dependent receptors with known specificity tend to import siderophores or vitamin B12. A TonB system and Tol-Pal system often will co-exist in a single bacterial genome. |
| Genome Property | GenProp0543: TonB-dependent transport (HMM) |
