HMM Summary Page: TIGR02801

Functionprotein TolR
Gene SymboltolR
Trusted Cutoff127.30
Domain Trusted Cutoff127.30
Noise Cutoff121.75
Domain Noise Cutoff121.75
Isology Typeequivalog
HMM Length129
Mainrole CategoryTransport and binding proteins
Subrole CategoryOther
Gene Ontology TermGO:0015078: hydrogen ion transmembrane transporter activity molecular_function
GO:0015992: proton transport biological_process
GO:0016044: cellular membrane organization biological_process
GO:0031237: intrinsic to external side of plasma membrane, in periplasmic space cellular_component
AuthorHaft DH
Entry DateJan 20 2006 3:28PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe model describes the inner membrane protein TolR, part of the TolR/TolQ complex that transduces energy from the proton-motive force, through TolA, to an outer membrane complex made up of TolB and Pal (peptidoglycan-associated lipoprotein). The complex is required to maintain outer membrane integrity, and defects may cause a defect in the import of some organic compounds in addition to the resulting morphologic. While several gene pairs homologous to talR and tolQ may be found in a single genome, but the scope of this model is set to favor finding only bone fide TolR, supported by operon structure as well as by score.
Genome PropertyGenProp0542: Tol-Pal system (HMM)