HMM Summary Page: TIGR02795

Functiontol-pal system protein YbgF
Gene SymbolygbF
Trusted Cutoff90.10
Domain Trusted Cutoff90.10
Noise Cutoff77.10
Domain Noise Cutoff77.10
Isology Typeequivalog
HMM Length119
AuthorHaft DH
Entry DateJan 19 2006 10:59AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are the product of one of seven genes regularly clustered in operons to encode the proteins of the tol-pal system, which is critical for maintaining the integrity of the bacterial outer membrane. The gene for this periplasmic protein has been designated orf2 and ybgF. All members of the seed alignment were from unique tol-pal gene regions from completed bacterial genomes. The architecture of this protein is a signal sequence, a low-complexity region usually rich in Asn and Gln, a well-conserved region with tandem repeats that resemble the tetratricopeptide (TPR) repeat, involved in protein-protein interaction.
ReferencesRN [1] RM 16207916 RT Tol-Pal proteins are critical cell envelope components of Erwinia chrysanthemi affecting cell morphology and virulence. RA Dubuisson JF, Vianney A, Hugouvieux-Cotte-Pattat N, Lazzaroni JC. RL Microbiology. 2005 Oct;151(Pt 10):3337-47.
Genome PropertyGenProp0542: Tol-Pal system (HMM)