HMM Summary Page: TIGR02792

Functionprotocatechuate 4,5-dioxygenase, alpha subunit
Gene SymbolligA
Trusted Cutoff108.60
Domain Trusted Cutoff108.60
Noise Cutoff43.75
Domain Noise Cutoff43.75
Isology Typeequivalog
EC Number1.13.11.8
HMM Length117
Mainrole CategoryEnergy metabolism
Subrole CategoryAerobic
Gene Ontology TermGO:0018579: protocatechuate 4,5-dioxygenase activity molecular_function
GO:0046278: protocatechuate metabolic process biological_process
AuthorHaft DH
Entry DateJan 16 2006 3:10PM
Last ModifiedFeb 14 2011 3:27PM
CommentProtocatechuate (PCA) 4,5-dioxygenase is the first enzyme in the PCA 4,5-cleavage pathway that is an alternative to PCA 3,4-cleavage and PCA 2,3 cleavage pathways. PCA is an intermediate in the breakdown of lignin (hence the gene symbol ligA) and other compounds. Members of this family are the alpha chain of PCA 4,5-dioxygenase, or the equivalent domain of a fusion protein.
ReferencesRN [1] RM 12486039 RT Characterization of the 4-carboxy-4-hydroxy-2-oxoadipate aldolase gene and operon structure of the protocatechuate 4,5-cleavage pathway genes in Sphingomonas paucimobilis SYK-6. RA Hara H, Masai E, Miyauchi K, Katayama Y, Fukuda M. RL J Bacteriol. 2003 Jan;185(1):41-50.