HMM Summary Page: TIGR02786

Functiondouble-strand break repair protein AddB
Gene SymboladdB
Trusted Cutoff486.50
Domain Trusted Cutoff486.50
Noise Cutoff458.40
Domain Noise Cutoff458.40
Isology Typeequivalog
HMM Length1024
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
Gene Ontology TermGO:0000724: double-strand break repair via homologous recombination biological_process
AuthorHaft DH
Entry DateJan 12 2006 8:41AM
Last ModifiedFeb 14 2011 3:27PM
CommentAddAB is a system well described in the Firmicutes as a replacement for RecBCD in many prokaryotes for the repair of double stranded break DNA damage. More recently, a distantly related gene pair conserved in many alphaproteobacteria was shown also to function in double-stranded break repair in Rhizobium etli. This family consists of AddB proteins of the alphaproteobacteial type.
ReferencesRN [1] RM 15547262 RT The recombination genes addAB are not restricted to gram-positive bacteria: genetic analysis of the recombination initiation enzymes RecF and AddAB in Rhizobium etli. RA Zuniga-Castillo J, Romero D, Martinez-Salazar JM. RL J Bacteriol. 2004 Dec;186(23):7905-13.
Genome PropertyGenProp0493: addAB pathway (HMM)