HMM Summary Page: TIGR02778

FunctionDNA ligase D, polymerase domain
Gene SymbolligD
Trusted Cutoff214.70
Domain Trusted Cutoff214.70
Noise Cutoff122.65
Domain Noise Cutoff122.65
Isology Typeequivalog_domain
HMM Length245
AuthorHaft DH
Entry DateJan 10 2006 1:21PM
Last ModifiedFeb 14 2011 3:27PM
CommentDNA repair of double-stranded breaks by non-homologous end joining (NHEJ) is accomplished by a two-protein system that is present in a minority of prokaryotes. One component is the Ku protein (see TIGR02772), which binds DNA ends. The other is a DNA ligase, a protein that is a multidomain polypeptide in most of those bacteria that have NHEJ, a permuted polypeptide in Mycobacterium tuberculosis and a few other species, and the product of tandem genes in some other bacteria. This model represents the polymerase domain.
Genome PropertyGenProp0492: nonhomologous end-joining, bacterial type (HMM)