HMM Summary Page: TIGR02775

FunctionP-type conjugative transfer protein TrbG
Gene SymboltrbG
Trusted Cutoff180.85
Domain Trusted Cutoff180.85
Noise Cutoff99.65
Domain Noise Cutoff99.65
Isology Typeequivalog
HMM Length206
Mainrole CategoryCellular processes
Subrole CategoryConjugation
Gene Ontology TermGO:0009291: unidirectional conjugation biological_process
AuthorSelengut J
Entry DateJan 10 2006 9:54AM
Last ModifiedFeb 14 2011 3:27PM
CommentThe TrbG protein is found in the trb locus of Agrobacterium Ti plasmids where it is involved in the type IV secretion system for plasmid conjugative transfer [1]. TrbG is a homolog of the F-type TraK protein (which is believed to be an outer membrane pore-forming secretin, TIGR02756) as well as the vir system VirB9 protein [2,3].
ReferencesRN [1] RM PMID: 8763953 RT The tra region of the nopaline-type Ti plasmid is a chimera with elements related to the transfer systems of RSF1010, RP4, and F. RA Farrand SK, Hwang I, Cook DM. RL J Bacteriol. 1996 Jul;178(14):4233-47. RN [2] RM PMID: 11722740 RA Harris RL, Hombs V, Silverman PM. RT Evidence that F-plasmid proteins TraV, TraK and TraB assemble into an envelope-spanning structure in Escherichia coli. RL Mol Microbiol. 2001 Nov;42(3):757-66. RN [3] RM PMID: 12855161 RT F factor conjugation is a true type IV secretion system. RA Lawley TD, Klimke WA, Gubbins MJ, Frost LS. RL FEMS Microbiol Lett. 2003 Jul 15;224(1):1-15.
Genome PropertyGenProp0485: F and P-type conjugation systems (type IV secretion), common components (HMM)