HMM Summary Page: TIGR02768

FunctionTi-type conjugative transfer relaxase TraA
Gene SymboltraA
Trusted Cutoff590.45
Domain Trusted Cutoff590.45
Noise Cutoff348.55
Domain Noise Cutoff348.55
Isology Typeequivalog
HMM Length751
AuthorSelengut J
Entry DateJan 6 2006 12:58PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein contains domains distinctive of a single strand exonuclease (N-terminus, MobA/MobL, PF03389) as well as a helicase domain (central region, homologous to the corresponding region of the F-type relaxase TraI, TIGR02760). This protein likely fills the same role as TraI(F), nicking (at the oriT site) and unwinding the coiled plasmid prior to conjugative transfer [1].
ReferencesRN [1] RM PMID: 8763953 RT The tra region of the nopaline-type Ti plasmid is a chimera with elements related to the transfer systems of RSF1010, RP4, and F. RA Farrand SK, Hwang I, Cook DM. RL J Bacteriol. 1996 Jul;178(14):4233-47.
Genome PropertyGenProp0490: Ti-type conjugation system (HMM)