HMM Summary Page: TIGR02759

Functiontype IV conjugative transfer system coupling protein TraD
Gene SymboltraD
Trusted Cutoff521.35
Domain Trusted Cutoff521.35
Noise Cutoff327.80
Domain Noise Cutoff327.80
Isology Typeequivalog
HMM Length566
AuthorSelengut J
Entry DateDec 23 2005 1:18PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe TraD protein performs an essential coupling function in conjugative type IV secretion systems. This protein sits at the inner membrane in contact with the assembled pilus and its scaffold as well as the relaxosome-plasmid DNA complex (through TraM) [1,2].
ReferencesRN [1] RM PMID: 15466052 RA Beranek A, Zettl M, Lorenzoni K, Schauer A, Manhart M, Koraimann G. RT Thirty-eight C-terminal amino acids of the coupling protein TraD of the F-like conjugative resistance plasmid R1 are required and sufficient to confer binding to the substrate selector protein TraM. RL J Bacteriol. 2004 Oct;186(20):6999-7006. RN [2] RM PMID: 16138100 RA Frost LS, Leplae R, Summers AO, Toussaint A. RT Mobile genetic elements: the agents of open source evolution. RL Nat Rev Microbiol. 2005 Sep;3(9):722-32.
Genome PropertyGenProp0485: F and P-type conjugation systems (type IV secretion), common components (HMM)