HMM Summary Page: TIGR02755

Functiontype-F conjugative transfer system pilin acetylase TraX
Gene SymboltraX
Trusted Cutoff149.35
Domain Trusted Cutoff149.35
Noise Cutoff104.70
Domain Noise Cutoff104.70
Isology Typeequivalog
EC Number2.3.1.-
HMM Length224
AuthorSelengut J
Entry DateDec 22 2005 9:26AM
Last ModifiedFeb 14 2011 3:27PM
CommentTraX is responsible for the acetylation of the F-pilin TraA during conjugative plasmid transfer. The purpose of this acetylation is unclear, but the reported transcriptional regulation of TraX may indicate that it is involved in the process of pilu extension/retraction [1,2,3].
ReferencesRN [1] RM PMID: 8444800 RA Moore D, Hamilton CM, Maneewannakul K, Mintz Y, Frost LS, Ippen-Ihler K. RT The Escherichia coli K-12 F plasmid gene traX is required for acetylation of F pilin. RL J Bacteriol. 1993 Mar;175(5):1375-83. RN [2] RM PMID: 7768788 RA Maneewannakul K, Maneewannakul S, Ippen-Ihler K. RT Characterization of traX, the F plasmid locus required for acetylation of F-pilin subunits. RL J Bacteriol. 1995 Jun;177(11):2957-64. RN [3] RM PMID: 16138100 RA Frost LS, Leplae R, Summers AO, Toussaint A. RT Mobile genetic elements: the agents of open source evolution. RL Nat Rev Microbiol. 2005 Sep;3(9):722-32.
Genome PropertyGenProp0484: F-type conjugation system (type IV secretion) specific components (HMM)