HMM Summary Page: TIGR02754

Functionnickel-type superoxide dismutase maturation protease
Gene SymbolsodX
Trusted Cutoff63.25
Domain Trusted Cutoff63.25
Noise Cutoff55.10
Domain Noise Cutoff55.10
Isology Typeequivalog
EC Number3.4.21.-
HMM Length90
Mainrole CategoryCellular processes
Subrole CategoryDetoxification
Gene Ontology TermGO:0004252: serine-type endopeptidase activity molecular_function
GO:0019430: removal of superoxide radicals biological_process
GO:0051605: protein maturation by peptide bond cleavage biological_process
AuthorHaft DH
Entry DateDec 22 2005 8:48AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are apparent proteases encoded adjacent to the genes for a nickel-type superoxide dismutase. This family belongs to the same larger family (see Pfam model PF00717) as signal peptidase I, an unusual serine protease suggested to have a Ser/Lys catalytic dyad.
ReferencesDR PFAM; PF00717; Peptidase S24-like domainRN [1] RM 15516600 RT In vivo production of active nickel superoxide dismutase from Prochlorococcus marinus MIT9313 is dependent on its cognate peptidase. RA Eitinger T. RL J Bacteriol. 2004 Nov;186(22):7821-5.
Genome PropertyGenProp0488: superoxide dismutase, nickel-type (HMM)