HMM Summary Page: TIGR02750

Functiontype-F conjugative transfer system mating-pair stabilization protein TraN
Gene SymboltraN
Trusted Cutoff422.45
Domain Trusted Cutoff422.45
Noise Cutoff247.45
Domain Noise Cutoff247.45
Isology Typeequivalog
HMM Length572
AuthorSelengut J
Entry DateDec 21 2005 12:28PM
Last ModifiedFeb 14 2011 3:27PM
CommentTraN is a large cysteine-rich outer membrane protein involved in the mating-pair stabilization (adhesin) component of the F-type conjugative plamid transfer system. TraN is believed to interact with the core type IV secretion system apparatus through the TraV protein [1,2,3].
ReferencesRN [1] RM PMID: 1593622 RA Maneewannakul S, Kathir P, Ippen-Ihler K. RT Characterization of the F plasmid mating aggregation gene traN and of a new F transfer region locus trbE. RL J Mol Biol. 1992 May 20;225(2):299-311. RN [2] RM PMID: 12855161 RA Lawley TD, Klimke WA, Gubbins MJ, Frost LS. RT F factor conjugation is a true type IV secretion system. RL FEMS Microbiol Lett. 2003 Jul 15;224(1):1-15. RN [3] RM PMID: 16138100 RA Frost LS, Leplae R, Summers AO, Toussaint A. RT Mobile genetic elements: the agents of open source evolution. RL Nat Rev Microbiol. 2005 Sep;3(9):722-32.
Genome PropertyGenProp0484: F-type conjugation system (type IV secretion) specific components (HMM)