HMM Summary Page: TIGR02747

Functiontype IV conjugative transfer system protein TraV
Gene SymboltraV
Trusted Cutoff44.75
Domain Trusted Cutoff44.75
Noise Cutoff37.25
Domain Noise Cutoff37.25
Isology Typeequivalog
HMM Length145
AuthorSelengut J
Entry DateDec 20 2005 10:53AM
Last ModifiedFeb 14 2011 3:27PM
CommentThe TraV protein is a component of conjugative type IV secretion systems. TraV is an outer membrane lipoprotein and is believed to interact with the secretin TraK [1,2,3]. The alignment contains three conserved cysteines in the N-terminal half.
ReferencesRN [1] RM PMID: 11722740 RT Evidence that F-plasmid proteins TraV, TraK and TraB assemble into an envelope-spanning structure in Escherichia coli. RA Harris RL, Hombs V, Silverman PM. RL Mol Microbiol. 2001 Nov;42(3):757-66. RN [2] RM PMID: 12855161 RA Lawley TD, Klimke WA, Gubbins MJ, Frost LS. RT F factor conjugation is a true type IV secretion system. RL FEMS Microbiol Lett. 2003 Jul 15;224(1):1-15. RN [3] RM PMID: 16138100 RA Frost LS, Leplae R, Summers AO, Toussaint A. RT Mobile genetic elements: the agents of open source evolution. RL Nat Rev Microbiol. 2005 Sep;3(9):722-32.
Genome PropertyGenProp0485: F and P-type conjugation systems (type IV secretion), common components (HMM)