HMM Summary Page: TIGR02745

Functioncytochrome c oxidase accessory protein CcoG
Gene SymbolccoG
Trusted Cutoff316.70
Domain Trusted Cutoff316.70
Noise Cutoff171.70
Domain Noise Cutoff171.70
Isology Typeequivalog
HMM Length435
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0008535: respiratory chain complex IV assembly biological_process
AuthorHaft DH
Entry DateDec 19 2005 2:04PM
Last ModifiedFeb 14 2011 3:27PM
CommentMember of this ferredoxin-like protein family are found exclusively in species with an operon encoding the cbb3 type of cytochrome c oxidase (cco-cbb3), and near the cco-cbb3 operon in about half the cases. The cco-cbb3 is found in a variety of proteobacteria and almost nowhere else, and is associated with oxygen use under microaerobic conditions. Some (but not all) of these proteobacteria are also nitrogen-fixing, hence the gene symbol fixG. FixG was shown essential for functional cco-cbb3 expression in Bradyrhizobium japonicum.
ReferencesRN [1] RM 8661920 RT The Bradyrhizobium japonicum fixGHIS genes are required for the formation of the high-affinity cbb3-type cytochrome oxidase. RA Preisig O, Zufferey R, Hennecke H. RL Arch Microbiol. 1996 May;165(5):297-305. RN [2] RM 1400197 RT Rhodobacter sphaeroides rdxA, a homolog of Rhizobium meliloti fixG, encodes a membrane protein which may bind cytoplasmic [4Fe-4S] clusters. RA Neidle EL, Kaplan S. RL J Bacteriol. 1992 Oct;174(20):6444-54.
Genome PropertyGenProp0483: cytochrome c oxidase, cbb3-type (HMM)