HMM Summary Page: TIGR02735

Functionphosphoribosylaminoimidazole-succinocarboxamide synthase
Gene SymbolpurC
Trusted Cutoff394.20
Domain Trusted Cutoff394.20
Noise Cutoff265.40
Domain Noise Cutoff265.40
Isology Typeequivalog
EC Number6.3.2.6
HMM Length365
Mainrole CategoryPurines, pyrimidines, nucleosides, and nucleotides
Subrole CategoryPurine ribonucleotide biosynthesis
Gene Ontology TermGO:0004639: phosphoribosylaminoimidazolesuccinocarboxamide synthase activity molecular_function
GO:0009152: purine ribonucleotide biosynthetic process biological_process
AuthorHaft DH
Entry DateDec 15 2005 1:27PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family appear to represent a novel form of phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase), significantly different in sequence and gap pattern from a form (see TIGR00081) shared by a broad range of bacteria and eukaryotes. Members of this family are found within the gammaproteobacteria in the genera Vibrio, Shewanella, and Colwellia, and also (reported as a fragment) in the primitive eukarote Guillardia theta.
References DR HAMAP; MF_00137; 5 of 333
Genome PropertyGenProp0110: purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate (HMM)