HMM Summary Page: TIGR02730

Functioncarotene isomerase
Gene SymbolcrtH
Trusted Cutoff586.90
Domain Trusted Cutoff586.90
Noise Cutoff296.40
Domain Noise Cutoff296.40
Isology Typeequivalog
EC Number5.-.-.-
HMM Length493
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryOther
Gene Ontology TermGO:0016117: carotenoid biosynthetic process biological_process
GO:0046608: carotenoid isomerase activity molecular_function
AuthorHaft DH
Entry DateDec 12 2005 11:53AM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family, including sll0033 (crtH) of Synechocystis sp. PCC 6803, catalyze a cis-trans isomerization of carotenes to the all-trans lycopene, a reaction that can also occur non-enzymatically in light through photoisomerization.
ReferencesRN [1] RM 15557094 RT Analysis in vitro of the enzyme CRTISO establishes a poly-cis-carotenoid biosynthesis pathway in plants. RA Isaacson T, Ohad I, Beyer P, Hirschberg J. RL Plant Physiol. 2004 Dec;136(4):4246-55. RN [2] RM 11773533 RT Identification of a gene required for cis-to-trans carotene isomerization in carotenogenesis of the cyanobacterium Synechocystis sp. PCC 6803. RA Masamoto K, Wada H, Kaneko T, Takaichi S. RL Plant Cell Physiol. 2001 Dec;42(12):1398-402.