HMM Summary Page: TIGR02726

Functionphenylphosphate carboxylase, delta subunit
Gene SymbolppcD
Trusted Cutoff281.95
Domain Trusted Cutoff281.95
Noise Cutoff178.85
Domain Noise Cutoff178.85
Isology Typeequivalog
HMM Length169
Mainrole CategoryEnergy metabolism
Subrole CategoryAnaerobic
AuthorHaft DH
Entry DateDec 7 2005 3:06PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are the alpha subunit of phenylphosphate carboxylase. Phenol (methyl-benzene) is converted to phenylphosphate, then para-carboxylated by this four-subunit enzyme, with the release of phosphate, to 4-hydroxybenzoate. The enzyme contains neither biotin nor thiamin pyrophosphate. This delta subunit belongs to HAD family hydrolases.
ReferencesRM 15231788 RT Phenylphosphate carboxylase: a new C-C lyase involved in anaerobic phenol metabolism in Thauera aromatica. RA Schuhle K, Fuchs G. RL J Bacteriol. 2004 Jul;186(14):4556-67.