HMM Summary Page: TIGR02724

Functionphenylphosphate carboxylase, beta subunit
Gene SymbolppcB
Trusted Cutoff468.95
Domain Trusted Cutoff468.95
Noise Cutoff386.30
Domain Noise Cutoff386.30
Isology Typeequivalog
HMM Length472
AuthorHaft DH
Entry DateDec 7 2005 1:06PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are the beta subunit of phenylphosphate carboxylase. Phenol (methyl-benzene) is converted to phenylphosphate, then para-carboxylated by this four-subunit enzyme, with the release of phosphate, to 4-hydroxybenzoate. The enzyme contains neither biotin nor thiamin pyrophosphate. This beta subunit is homologous to the alpha subunit and, more broadly, to UbiD family decarboxylases.
ReferencesRM 15231788 RT Phenylphosphate carboxylase: a new C-C lyase involved in anaerobic phenol metabolism in Thauera aromatica. RA Schuhle K, Fuchs G. RL J Bacteriol. 2004 Jul;186(14):4556-67.