HMM Summary Page: TIGR02720
Accession | TIGR02720 |
Name | pyruv_oxi_spxB |
Function | pyruvate oxidase |
Gene Symbol | spxB |
Trusted Cutoff | 637.85 |
Domain Trusted Cutoff | 637.85 |
Noise Cutoff | 455.90 |
Domain Noise Cutoff | 455.90 |
Isology Type | equivalog |
EC Number | 1.2.3.3 |
HMM Length | 575 |
Mainrole Category | Energy metabolism |
Subrole Category | Aerobic |
Gene Ontology Term | GO:0009444: pyruvate oxidation biological_process |
GO:0047112: pyruvate oxidase activity molecular_function | |
Author | Haft DH |
Entry Date | Dec 5 2005 9:55AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Members of this family are examples of pyruvate oxidase (EC 1.2.3.3), an enzyme with FAD and TPP as cofactors that catalyzes the reaction pyruvate + phosphate + O2 + H2O = acetyl phosphate + CO2 + H2O2. It should not be confused with pyruvate dehydrogenase [cytochrome] (EC 1.2.2.2) as in E. coli PoxB, although the E. coli enzyme is closely homologous and has pyruvate oxidase as an alternate name. |
References | RN [1] RM 15175288 RT Characterization and functional analysis of the poxB gene, which encodes pyruvate oxidase in Lactobacillus plantarum. RA Lorquet F, Goffin P, Muscariello L, Baudry JB, Ladero V, Sacco M, Kleerebezem M, Hols P. RL J Bacteriol. 2004 Jun;186(12):3749-59. |