HMM Summary Page: TIGR02714

Functionring-opening amidohydrolases
Trusted Cutoff153.10
Domain Trusted Cutoff153.10
Noise Cutoff81.05
Domain Noise Cutoff81.05
Isology Typesubfamily
EC Number3.5.2.-
HMM Length366
Gene Ontology TermGO:0016812: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides molecular_function
AuthorHaft DH
Entry DateDec 1 2005 3:33PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family are are ring-opening amidohydrolases, including cyanuric acid amidohydrolase (EC (AtzD and TrzD) and barbiturase. Note that barbiturase does not act as defined for EC (barbiturate + water = malonate + urea) but rather catalyzes the ring-opening of barbituric acid to ureidomalonic acid (see Soong, et al., PMID:11485332).