| Accession | TIGR02712 |
| Name | urea_carbox |
| Function | urea carboxylase |
| Gene Symbol | uca |
| Trusted Cutoff | 1303.85 |
| Domain Trusted Cutoff | 1303.85 |
| Noise Cutoff | 655.90 |
| Domain Noise Cutoff | 655.90 |
| Isology Type | equivalog |
| EC Number | 6.3.4.6 |
| HMM Length | 1201 |
| Mainrole Category | Central intermediary metabolism |
| Subrole Category | Nitrogen metabolism |
| Gene Ontology Term | GO:0004847: urea carboxylase activity molecular_function |
| | GO:0019627: urea metabolic process biological_process |
| Author | Haft DH |
| Entry Date | Dec 1 2005 8:26AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this family are ATP-dependent urea carboxylase, including characterized members from Oleomonas sagaranensis (alpha class Proteobacterium) and yeasts such as Saccharomyces cerevisiae. The allophanate hydrolase domain of the yeast enzyme is not included in this model and is represented by an adjacent gene in Oleomonas sagaranensis. The fusion of urea carboxylase and allophanate hydrolase is designated urea amidolyase. The enzyme from Oleomonas sagaranensis was shown to be highly active on acetamide and formamide as well as urea. |
| References | RM 15090492
RT Enzymatic characterization of a prokaryotic urea carboxylase.
RA Kanamori T, Kanou N, Atomi H, Imanaka T.
RL J Bacteriol. 2004 May;186(9):2532-9. |
| Genome Property | GenProp0481: urea carboxylase/allophanate hydrolase pathway (HMM) |
