| Accession | TIGR02702 |
| Name | SufR_cyano |
| Function | iron-sulfur cluster biosynthesis transcriptional regulator SufR |
| Gene Symbol | sufR |
| Trusted Cutoff | 178.80 |
| Domain Trusted Cutoff | 178.80 |
| Noise Cutoff | 141.35 |
| Domain Noise Cutoff | 141.35 |
| Isology Type | equivalog |
| HMM Length | 208 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Other |
| Gene Ontology Term | GO:0016226: iron-sulfur cluster assembly biological_process |
| | GO:0030528: transcription regulator activity molecular_function |
| | GO:0045449: regulation of transcription biological_process |
| Author | Haft DH |
| Entry Date | Nov 23 2005 11:02AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | All members of this cyanobacterial protein family are the transcriptional regulator SufR and regulate the SUF system, which makes possible iron-sulfur cluster biosynthesis despite exposure to oxygen. In all cases, the sufR gene is encoded near SUF system genes but in the opposite direction. This DNA-binding protein belongs to the the DeoR family of helix-loop-helix proteins. All members also have a probable metal-binding motif C-X(12)-C-X(13)-C-X(14)-C near the C-terminus. |
| References | RM 14761990
RT The sufR gene (sll0088 in Synechocystis sp. strain PCC 6803) functions as a repressor of the sufBCDS operon in iron-sulfur cluster biogenesis in cyanobacteria.
RA Wang T, Shen G, Balasubramanian R, McIntosh L, Bryant DA, Golbeck JH.
RL J Bacteriol. 2004 Feb;186(4):956-67. |
| Genome Property | GenProp0137: iron-sulfur cluster assembly SUF system (HMM) |
