HMM Summary Page: TIGR02694

Functionarsenite oxidase, small subunit
Trusted Cutoff95.65
Domain Trusted Cutoff95.65
Noise Cutoff61.70
Domain Noise Cutoff61.70
Isology Typeequivalog
EC Number1.20.9.1
HMM Length129
Mainrole CategoryEnergy metabolism
Subrole CategoryElectron transport
AuthorHaft DH
Entry DateNov 17 2005 8:45AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents the small subunit of an arsenite oxidase complex. It is a Rieske protein and appears to rely on the Tat (twin-arginine translocation) system to cross the membrane. Although this enzyme could run in the direction of arsenate reduction to arsenite in principle, the relevant biological function is arsenite oxidation for energy metabolism, not arsenic resistance. Homologs to both large (TIGR02693) and small subunits that score in the gray zone between the set trusted and noise bit score cutoffs for the respective models are found in Aeropyrum pernix K1 and in Sulfolobus tokodaii str. 7.
ReferencesDR PFAM; PF00355; Rieske [2Fe-2S] domain RN [1] RM 12679550 RT Arsenite oxidase, an ancient bioenergetic enzyme. RA Lebrun E, Brugna M, Baymann F, Muller D, Lievremont D, Lett MC, Nitschke W. RL Mol Biol Evol. 2003 May;20(5):686-93.
Genome PropertyGenProp0473: arsenite oxidase (HMM)