HMM Summary Page: TIGR02684

Functionprobable addiction module antidote protein
Trusted Cutoff53.70
Domain Trusted Cutoff53.70
Noise Cutoff37.10
Domain Noise Cutoff37.10
Isology Typehypoth_equivalog
HMM Length89
Mainrole CategoryMobile and extrachromosomal element functions
Subrole CategoryOther
AuthorHaft DH
Entry DateNov 9 2005 4:07PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this strictly bacterial protein family are small, at roughly 100 amino acids. The gene is almost invariably the downstream member of a gene pair. It is a predicted DNA-binding protein from a clade within Pfam helix-turn-helix family PF01381. These gene pairs, when found on the bacterial chromosome, are located often with prophage regions, but also both in integrated plasmid regions and in housekeeping gene regions. Analysis suggests that the gene pair may serve as an addiction module.
ReferencesDR PFAM; PF01381; HTH_3; Helix-turn-helix
Genome PropertyGenProp0471: uncharacterized gene pair TIGR02683/TIGR02684 (HMM)