Accession | TIGR02669 |
Name | SpoIID_LytB |
Function | SpoIID/LytB domain |
Trusted Cutoff | 83.30 |
Domain Trusted Cutoff | 83.30 |
Noise Cutoff | 37.35 |
Domain Noise Cutoff | 37.35 |
Isology Type | domain |
HMM Length | 270 |
Mainrole Category | Unknown function |
Subrole Category | General |
Gene Ontology Term | GO:0003674: molecular_function molecular_function |
| GO:0005575: cellular_component cellular_component |
| GO:0008150: biological_process biological_process |
Author | Haft DH |
Entry Date | Sep 27 2005 11:53AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This model describes a domain found typically in two or three proteins per genome in Cyanobacteria and Firmicutes, and sporadically in other genomes. One member is SpoIID of Bacillus subtilis. Another in B. subtilis is the C-terminal half of LytB, encoded immediately upstream of an amidase, the autolysin LytC, to which its N-terminus is homologous. Gene neighborhoods are not well conserved for members of this family, as many, such as SpoIID, are monocistronic. One early modelling-based study suggests a DNA-binding role for SpoIID, but the function of this domain is unknown. |
References | RN [1]
RM 1357079
RT Sequencing and analysis of the Bacillus subtilis lytRABC divergon: a regulatory unit encompassing the structural genes of the N-acetylmuramoyl-L-alanine amidase and its modifier.
RA J Gen Microbiol. 1992 Sep;138(9):1949-61.
RN [2]
RM 3129534
RT The possible DNA-binding nature of the regulatory proteins, encoded by spoIID and gerE, involved in the sporulation of Bacillus subtilis.
RA Holland SK, Cutting S, Mandelstam J.
RL J Gen Microbiol. 1987 Sep;133(9):2381-91. |