HMM Summary Page: TIGR02667

Functionmolybdenum cofactor biosynthesis protein B
Gene SymbolmoaB
Trusted Cutoff222.40
Domain Trusted Cutoff222.40
Noise Cutoff177.50
Domain Noise Cutoff177.50
Isology Typeequivalog
HMM Length163
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryMolybdopterin
Gene Ontology TermGO:0003824: catalytic activity molecular_function
GO:0006777: Mo-molybdopterin cofactor biosynthetic process biological_process
AuthorHaft DH
Entry DateSep 21 2005 11:48AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents the MoaB protein molybdopterin biosynthesis regions in Proteobacteria. This crystallized but incompletely characterized protein is thought to be involved in, though not required for, early steps in molybdopterin biosynthesis. It may bind a molybdopterin precursor. A distinctive conserved motif PCN near the C-terminus helps distinguish this clade from other homologs, including sets of proteins designated MogA.
ReferencesRN [1] RM 15269205 RT The crystal structure of Escherichia coli MoaB suggests a probable role in molybdenum cofactor synthesis. RA Sanishvili R, Beasley S, Skarina T, Glesne D, Joachimiak A, Edwards A, Savchenko A. RL J Biol Chem. 2004 Oct 1;279(40):42139-46.
Genome PropertyGenProp0466: molybdopterin biosynthesis (HMM)