HMM Summary Page: TIGR02636

Functiongalactose mutarotase
Gene SymbolgalM
Trusted Cutoff397.65
Domain Trusted Cutoff397.65
Noise Cutoff346.80
Domain Noise Cutoff346.80
Isology Typeequivalog
EC Number5.1.3.3
HMM Length336
Gene Ontology TermGO:0004034: aldose 1-epimerase activity molecular_function
GO:0006012: galactose metabolic process biological_process
AuthorHaft DH
Entry DateJul 28 2005 4:06PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family act as galactose mutarotase (D-galactose 1-epimerase) and participate in the Leloir pathway for galactose/glucose interconversion. All members of the seed alignment for this model are found in gene clusters with other enzymes of the Leloir pathway. This enzyme family belongs to the aldose 1-epimerase family, described by Pfam HMM PF01263. However, the enzyme described as aldose 1-epimerase itself (EC is called broadly specific for D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose. The restricted genome context for genes in this family suggests members should act primarily on D-galactose.
Genome PropertyGenProp0143: Leloir pathway (galactose/glucose interconversion) (HMM)