HMM Summary Page: TIGR02601

Functionautotransporter-associated beta strand repeat
Trusted Cutoff19.85
Domain Trusted Cutoff19.85
Noise Cutoff16.05
Domain Noise Cutoff16.05
Isology Typerepeat
HMM Length32
AuthorHaft DH
Entry DateJun 8 2005 3:01PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represent a core 32-residue region of a class of bacterial protein repeat found in one to 30 copies per protein. Most proteins with a copy of this repeat have domains associated with membrane autotransporters (PF03797, TIGR01414). The repeats occur with a periodicity of 60 to 100 residues. A pattern of sequence conservation is that every second residue is well-conserved across most of the domain. Pfam model PF05594 is based on a longer, much more poorly conserved multiple sequence alignment and hits some of the same proteins as this model with some overlap between the hit regions of the two models. It describes these repeats as likely to have a beta-helical structure.
ReferencesDR PFAM; PF05594; Haemagluttinin repeat DR SCOP; b.80.1.7; Virulence factor P.69 pertactin