| Accession | TIGR02583 |
| Name | DevR_archaea |
| Function | CRISPR-associated protein Cas7/Csa2, subtype I-A/APERN |
| Gene Symbol | cas7a |
| Trusted Cutoff | 212.60 |
| Domain Trusted Cutoff | 212.60 |
| Noise Cutoff | 107.40 |
| Domain Noise Cutoff | 107.40 |
| Isology Type | exception |
| HMM Length | 284 |
| Mainrole Category | Mobile and extrachromosomal element functions |
| Subrole Category | Other |
| Gene Ontology Term | GO:0003674: molecular_function molecular_function |
| | GO:0043571: maintenance of CRISPR repeat elements biological_process |
| Author | Selengut J |
| Entry Date | May 12 2005 1:25PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This HMM represents one such family, typified by MJ0381 of Methanococcus jannaschii. This archaeal clade is a member of the DevR family (TIGR01875) which includes the DevR protein of Myxococcus xanthus, a protein whose expression appears to regulated through a number of means, including both location and autorepression; DevR mutants are incapable of fruiting body development [1]. This subfamily is found in a CRISPR/Cas locus we designate APERN, so the family is designated Csa2, for CRISPR/Cas Subtype Protein 2. |
| References | DR URL http://www.tigr.org/tigr-scripts/CMR2/genome_property_def.spl?prop=2003
DR URL http://www.tigr.org/tigr-scripts/CMR2/genome_property_def.spl?prop=57306
RN [1]
RT A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/cas subtypes exist in prokaryotic genomes
RA Haft DH, Selengut JD, Mongodin EF, Nelsen KE
RL PLOS Comput. Biol. 1(6), e60-e69, 2005
RN [2]
RM 11788711
RT A DNA repair system specific for thermophilic Archaea and bacteria predicted by genomic context analysis.
RA Makarova KS, Aravind L, Grishin NV, Rogozin IB, Koonin EV.
RL Nucleic Acids Res. 2002 Jan 15;30(2):482-96 |
| Genome Property | GenProp0319: CRISPR system, I-A/Apern subtype (HMM) |
| | GenProp0021: CRISPR region (HMM) |
