| Accession | TIGR02563 |
| Name | cas_Csy4 |
| Function | CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST |
| Gene Symbol | cas6f |
| Trusted Cutoff | 36.25 |
| Domain Trusted Cutoff | 36.25 |
| Noise Cutoff | 29.30 |
| Domain Noise Cutoff | 29.30 |
| Isology Type | equivalog |
| EC Number | 3.1.-.- |
| HMM Length | 184 |
| Mainrole Category | Mobile and extrachromosomal element functions |
| Subrole Category | Other |
| Gene Ontology Term | GO:0003674: molecular_function molecular_function |
| | GO:0043571: maintenance of CRISPR repeat elements biological_process |
| Author | Haft DH |
| Entry Date | Apr 25 2005 12:53PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2462 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. This family is designated Csy4, for CRISPR/Cas Subtype Ypest protein 4. |
| References | DR URL http://www.tigr.org/tigr-scripts/CMR2/genome_property_def.spl?prop=2003
DR URL http://www.tigr.org/tigr-scripts/CMR2/genome_property_def.spl?prop=57298
RN [1]
RT A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/cas subtypes exist in prokaryotic genomes
RA Haft DH, Selengut JD, Mongodin EF, Nelsen KE
RL PLOS Comput. Biol. 1(6), e60-e69, 2005
RN [2]
RM PMID:22522703
RT Csy4 relies on an unusual catalytic dyad to position and cleave CRISPR RNA.
RA Haurwitz RE, Sternberg SH, Doudna JA
RL EMBO J. 2012 Apr 20;31(12):2824-32. |
| Genome Property | GenProp0310: CRISPR system, I-F/Ypest subtype (HMM) |
| | GenProp0021: CRISPR region (HMM) |
