HMM Summary Page: TIGR02548

FunctionCRISPR type I-E/ECOLI-associated protein CasB/Cse2
Gene SymbolcasB
Trusted Cutoff42.55
Domain Trusted Cutoff42.55
Noise Cutoff27.50
Domain Noise Cutoff27.50
Isology Typeequivalog
HMM Length159
Mainrole CategoryMobile and extrachromosomal element functions
Subrole CategoryOther
Gene Ontology TermGO:0003674: molecular_function molecular_function
GO:0043571: maintenance of CRISPR repeat elements biological_process
AuthorHaft DH
Entry DateApr 14 2005 12:21PM
Last ModifiedFeb 14 2011 3:27PM
CommentCRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This HMM family is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It was designated Cse2 originally, and renamed CasB based on its characterization in the CASCADE complex.
ReferencesDR URL DR URL RN [1] RT A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/cas subtypes exist in prokaryotic genomes RA Haft DH, Selengut JD, Mongodin EF, Nelsen KE RL PLOS Comput. Biol. 1(6), e60-e69, 2005 RN [2] RM PMID:18703739 RT Small CRISPR RNAs guide antiviral defense in prokaryotes. RA Brouns SJ, Jore MM, Lundgren M, Westra ER, Slijkhuis RJ, Snijders AP, Dickman MJ, Makarova KS, Koonin EV, van der Oost J RL Science. 2008 Aug 15;321(5891):960-4.
Genome PropertyGenProp0315: CRISPR system, I-E/Ecoli subtype (HMM)
GenProp0021: CRISPR region (HMM)