HMM Summary Page: TIGR02538

Functiontype IV-A pilus assembly ATPase PilB
Gene SymbolpilB
Trusted Cutoff675.65
Domain Trusted Cutoff675.65
Noise Cutoff625.75
Domain Noise Cutoff625.75
Isology Typeequivalog
HMM Length564
Mainrole CategoryCell envelope
Subrole CategorySurface structures
Gene Ontology TermGO:0008565: protein transporter activity molecular_function
GO:0009297: pilus assembly biological_process
GO:0016887: ATPase activity molecular_function
AuthorHaft DH
Entry DateMar 24 2005 9:32AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model describes a protein of type IV pilus biogenesis designated PilB in Pseudomonas aeruginosa but PilF in Neisseria gonorrhoeae; the more common usage, reflected here, is PilB. This protein is an ATPase involved in protein export for pilin assembly and is closely related to GspE (TIGR02533) of type II secretion, also called the main terminal branch of the general secretion pathway. Note that type IV pilus systems are often divided into type IV-A and IV-B, with the latter group including bundle-forming pilus, mannose-sensitive hemagglutinin, etc. Members of this family are found in type IV-A systems.
ReferencesRN [1] RM 8100347 RT Conservation of genes encoding components of a type IV pilus assembly/two-step protein export pathway in Neisseria gonorrhoeae. RA Lauer P, Albertson NH, Koomey M. RL Mol Microbiol. 1993 Apr;8(2):357-68.